Microtubules regulate angiotensin II type receptor and Rac1 localization in caveolae/lipid rafts: role in redox signaling: Retraction.
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The Emory University Investigation Committee also conducted an institutional investigation of fraudulent data published in Zuo et al. Arterioscler Thromb Vasc Biol. 2004:24;1223–1228. Emory University Office of Research Compliance reported that the Emory University Investigation Committee was unable to attribute responsibility for the image manipulation to any specific individual. Figures found to be manipulated were: 1A, 1B bottom panels, 2B middle panel and 4A top panel.
منابع مشابه
Microtubules regulate angiotensin II type 1 receptor and Rac1 localization in caveolae/lipid rafts: role in redox signaling.
OBJECTIVE Microtubules are important in signal transduction temporal-spatial organization. Full expression of angiotensin II (Ang II) signaling in vascular smooth muscle cells (VSMCs) is dependent on the reactive oxygen species (ROS) derived from nicotinamide-adenine dinucleotide phosphate (NAD(P)H) oxidase and the dynamic association of the Ang II type 1 receptor (AT1R) with caveolae/lipid raf...
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OBJECTIVE Angiotensin II (Ang II) is a potent mediator of vascular hypertrophy in vascular smooth muscle cells (VSMCs). These effects are mediated through the Ang II type 1 receptor (AT1R) and require its trafficking through caveolin-1 (Cav1)-enriched lipid rafts and reactive oxygen species (ROS) derived from Rac1-dependent NAD(P)H oxidase. The specific role(s) of Cav1 in AT1R signaling is inco...
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عنوان ژورنال:
- Arteriosclerosis, thrombosis, and vascular biology
دوره 31 5 شماره
صفحات -
تاریخ انتشار 2011